Also consider checking with any of the colon cancer advocate groups as they often know what combo of drugs are working. But if you are at a well known cancer center you should be in good hands.
- Overland Park, KS
- Member Since May 2013
Their Diagnoses (1)
- Family/Friend: Adenocarcinoma, Colorectal Cancer
- Patient Info: Newly diagnosed (has not begun treatment), Diagnosed: over 3 years ago, Female, Age: 68, KRAS mutation positive: Don't Know, BRAF mutation positive: Don't Know, Stage IV
- View this journey (0 Experiences)
hzk started followingover 3 years ago
Metastatic Colorectal Cancer: clinical research study question
Below is list of everyone on WhatNext who is living with colon cancer who has participated in a clinical trial. I would recommend reading through some of their experiences and then maybe even reaching out to the ones that you think might be most applicable to your situation.
Wishing you and your Mom the best.
Folfox + Bevacizumab and Folfiri + Bevacizumab are common chemo protocols for Stage 4 colorectal, usually the folfox is done first; then if that stops working, the folfiri, tho some start directly with folfiri.
Folfoxiri/Bevacizumab combines both Folfox and Folfiri, and should be as least as effective as either one alone. I assume your mom has to agree to the clinical trial and will be assigned one of the groups, as opposed to selecting. As Folfox/Bevacizumab is currently a standard treatment, I don't see any risks to participating in this trial. If she doesn't participate, she'll probably get Folfox/Bevacizumab. The trial is to see if adding the irinitocan to the mix enhances the effectiveness. With the exception of the difference in side effects, I don't see any negatives about going into this study.
Your mother will be receiving no less than the standard of care for Stage IV metastatic colon cancer.
Just my 2 cents.