The effect of cancer on relationships is profound. I find myself as the spouse of a three time cancer victim being angry most of the time. My anger is not logical: it's just there. I'm angry that my husband can't work, he is very sick, he has chemo brain and I feel overwhelmed. Of course, my anger is all about me and it is selfish and a completely useless emotion. But, it's always there; just like the cancer is. I have learned to accept the anger is going to be with me for a good, long while.