What kind of difficulty are you having with Temodar? Is it fatigue? nausea? I have taken Temodar MANY times over my 18+ year journey. I was one of the original test subjects on it in the mid-90s. I've found it is a little easier to take if you take it with lemon-lime soda as opposed to water. The capsule doesn't stick to your tongue and throat like it does with water. Taking it with clear soda also helps with that nasty chemical smell.
Zofran worked well for nausea for me, but if it does not work for you, I recommend asking your doctor for Emend and Kytril. I hated the constipation fac tor with both Temodar and the anti-nausea med, so stay hydrated with plenty of fluids and add extra fiber to your diet.
Are you working right now? Is your employer accommodating you as needed?