• Paty's Avatar

    Paty asked a questionColorectal (Colon) Cancer

    Has anyone taken xeloda and oxilaplatin together?

    • booboo's Avatar
      booboo

      I took those two drugs together briefly. I was to do 4 rounds as follows: An infusion of oxilaplatin and 2 weeks of daily xeloda, then a week off both drugs. I completed one round but then my doctor discontinued the xeloda because I just could not tolerate the drug. After discontinuing the xeloda I completed the oxilaplatin as scheduled.

      Xeloda made me horribly sick. When my surgeon saw me for a follow-up visit after the first round of xeloda, he told me I had lost too much weight (I was losing almost 2 lbs. per day) and recommemded to the medical oncologist that we stop chemo altogether. We compromised by stopping the xeloda and continuing with the infusions.

      over 4 years ago
    • Rosa's Avatar
      Rosa

      Yes I did. Four doses of oxilaplatin in six weeks. Two Xeloda pills twice a day from Monday to Friday on radiation days. The last two weeks my onc reduced them to one pill twice a day. The combination of all three did a number on my stomach. Heavy diarrhea, which caused killer hemorrhoids, and horrible cramps. I lost 20 pounds in the 6 weeks. Xeloda caused my hands and feet to turn dark, but no pain or bleeding (back to normal in a few weeks after finishing treatment).
      But all was worthwhile, my tumor (stage II) disappeared without surgery.
      Right now I am in my first year round of studies, labs, tests and so far everything is good. No sign of any tumor. Waiting for the results of the CT scan and the labs.
      Wish all the best to you.
      Be brave, be hopeful
      Blessings

      over 4 years ago
    • Elinwill's Avatar
      Elinwill

      Hi Paty, my husband has both of these drugs. He has had great results while on the chemo. Tumours shrunk and not too many side effects. He had no sickness or mouth ulceration, only the tingly hands and feet. He has been on them on and off for the past two years.

      over 4 years ago
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