• Poliana's Avatar

    Poliana shared an experience

    Drug or Chemo Therapy: About my dad:

    His PSA went up to 70 in december after receiving ketoconazole for two months. Doctor said he had to continue with ketoconazole for at least one month more.

    In January he repeated PSA and it went up to 109, then he started a radio therapy in L1 wich was one of the three points where he had mets.

    Now PSA went down to 94 (Doctor says that it is going to reduce more in 50 days after radio), but scans showed three new mets in spine (Little and no symptons by now, but they are there...) and one in the left leg (Femur) and difficulties to pee (He wakes up a lot at night and is tired because that. This is his biggest problem).

    Prostate weight is almost 200 grams.

    Doctor is wondering to indicate treatment with docetaxel now.

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    Poliana asked a questionProstate Cancer

    Benefits of docetaxel

    • nancyjac's Avatar
      nancyjac

      Doxetaxel (trade name Taxotere) is a commonly used chemotherapy drug for several types of cancer. I had Taxotere infusions for my inflammatory breast cancer. The only benefit of this and all chemotherapy drugs is to kill cancer cells. I took for 4 months and it prevented the cancer cells from spreading through both my lymph and vascular systems and reduced the total size of the cancer so that I was able to be in remission after a subsequent mastectomy.

      about 4 years ago
    • mgm48's Avatar
      mgm48

      My experience was to have my PSA drop from 99 to 36 from May 10 to August 23. While mine did not stay lowered as long as the onc expected it was a good 4 months of fighting my cancer and we move on.

      Keep it positive and smile :)

      about 4 years ago
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    Poliana asked a questionProstate Cancer

    Difficult to urinate

    • nancyjac's Avatar
      nancyjac

      I don't know that this is specifically related to prostate cancer, or any type of cancer for that matter. I get up at least twice every night, sometimes more, to urinate and have been for years. I'm able to go right back to sleep so it isn't a problem for me. I think as we get older, our bladders get a bit weaker. We also need to take in more fluids to stay well hydrated and that is going to translate to more frequent urination.

      The blood in his urine is another matter entirely and needs to be checked out.

      about 4 years ago
    • tomget's Avatar
      tomget

      I suppose you really need a urologist to evaluate ..if possible. But its my understanding that .. in general.. as we age and the prostrate enlarges...it can in most of us somewhat squeeze the urinary track and cause all kinds of problems. Similar to what your describing. But I guess its not caused by cancer but by the enlargement of the prostrate.

      And there are repairs that can be made. I forget the name but there is surgery to relieve this condition if it gets bad enough. I forget what its called. Some people with prostrate cancer can urinate just fine and some not.

      But I've heard doctors discuss the conditions your describing and they suggest that these things are not necessarily caused by prostrate cancer..whether its present or not..but by other things. Even the blood is not necessarily abnormal or a problem.

      Only a doctor could probably really answer this for you.

      Goodluck

      about 4 years ago
    • ROBERT's Avatar
      ROBERT (Best Answer!)

      Your father needs to see a urologist as soon as possible. They need to do a rectal digital exam to confirm any abnormality. Combined with a psa blood test this will tell them if he needs to have a biobsy and if they detect a posiblity of cancer. In my case my psa was normal but the exam showed a concern for cancer as it was hard which is a sign. I was getting up twice a night for almost a year which was normal if you have bengn prostate growth but the signs are similar to cancer. Early detection is the key for a better outcome. I wish I would have been quicker to see a urologist because it can spread very quickly as it did in my case. Blood is not normal and is also a concern in itself to see a urologist...dont wait.

      almost 4 years ago
  • Poliana's Avatar

    Poliana asked a questionProstate Cancer

    Even in a situation in wich PSA is increasing, can be considered a good news if this increse is getting more slow ?

    • nancyjac's Avatar
      nancyjac

      The rate of increase in PSA over time is called velocity or PSAV. A low rate of increase over time is good, but generally the standard for that is an increase of less than 4 over the course of a year. Many things can affect PSA values temporarily at any given time, so an average percent change per week is probably of little value.

      about 4 years ago
    • notwillie's Avatar
      notwillie

      From our experience, it is likely your dad's body is beginning to resist the particular medications he is on. DO not despair. There are others out there and also new drugs coming to market every day. Did they stage your dad's cancer? My husband is in stage IV and has no pain. They tell me it is not uncommon. Hoping for a good report on your dad sometime soon.

      about 4 years ago
    • mgm48's Avatar
      mgm48

      Nancyjac and notwillie are correct. As the PSA goes up it is just an indication that there is some activity. There are several things in your future. I'm currently recovering from a side effect of the trial drug I've been on. So I'm on hold - no drugs probably for a couple weeks. In this disease I've found that a week is nothing, a month is not much more and we fight on. Be patient and yes the lower velocity is good but don't get too caught up in it.

      Keep it positive and smile :)

      about 4 years ago