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    wildergal asked a questionColorectal (Colon) Cancer

    Xeloda Side Effects

    7 answers
    • booboo's Avatar
      booboo

      I agree that with a lymph node positive you should seriously consider taking Xeloda. But be aware that this drug can have some really harsh side effects. I had stage 3c rectal cancer. After lots of chemo and radiation, and surgery to remove the tumor, my oncologist put me on a regimen of Oxilaplatin and Xeloda. I was 46 at the time, and because of some positive lymph nodes my team recommended adjuvant treatment. I agreed, but I could not tolerate the Xeloda. It made me so sick that I was losing weight at the rate of more than a pound a day. After one round of the new treatment, (Oxilaplatin infusion followed by 14 days of Xeloda, a week off and then repeat) my surgeon and my oncologist were so alarmed by the weight loss that they took me off the Xeloda and we continued with just the Oxilaplatin infusions. That was in 2004, and I am cancer free today.

      Everyone is different. Discuss this with your doctor and, if necessary, seek a second opinion. Best of luck to you, whatever you decide.

      over 5 years ago
    • GolfGirl's Avatar
      GolfGirl

      No brainier for me - take the Xeloda. I also had 1of 14 nodes test positive and my oncologist ordered 12 rounds of Folfox + 5FU. My first go around I was on folfox + Xeloda and recall having more side effects from the oxilaplatin than from Xeloda - as the saying goes "everyone is different". It's a big decision and you will do what it right for you. Best of luck!

      over 5 years ago
    • Peroll's Avatar
      Peroll

      When I was stage III my oncologist told me that the probability of my cancer returning without any chemotherapy was 50% and 5% with chemo. Xeloda is a pill form of 5FU making it much easier to take, no days spent in the infusion center. I am currently on Xeloda and have been on 5FU (IV) before. The Xeloda has fewer and less sever side effects because it goes in slower.

      The problem you face is that it only takes a single surviving cancer cell to have it come back. A 1 mm tumor has a billion cell in it and a tumor has to be at least 4 to 5 mm to be seen on CT or PET scans. That means things advance quite a bit if you just wait and monitor. Chemo works best on small tumors so I highly recommend taking it now, for a few months, in hopes you will kill any of those pesky little cancer cells that may be lurking inside you. Good Luck

      over 5 years ago
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    wildergal shared an experience

    Other Care (Psychosocial): Wonderful co-counseling with my PCP. I feel it is mandatory for partner to be on board with Whatever treatment decision you make.

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    wildergal shared an experience

    Procedure or Surgery (Colon surgery (colectomy or hemicolectomy)): had laparoscopic colectomy 10/29. Back in action 2 weeks post-op. Thanks Dr. Mahdavian!

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    wildergal shared an experience

    Decision Point (chemo or no chemo): still in decision mode re chemotherapy following dx of Stage III CRC with "low grade" cells in 1 or 14 nodes.

    1 Comment
    • Gmo's Avatar
      Gmo

      I did chemo pills (Xeloda) with radiation and did not tolerate it well. Though not sure which side effects went to which tx. Still have to do chemo for 4-5months after surgery that's scheduled next month. Good luck.

      over 5 years ago
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